Suppliers

www.alcheminternational.com

Alchem International Ltd is exclusively dedicated to the manufacture of phyto-chemicals for medicinal and cosmetic use.

Technological capability and prowess ensures extraction of an isolated active molecule from a biomass of extract. For end-to end need for bulk drugs, we would be a one-stop shop for pharmaceutical ingredients, cosmetic, Nutraceutical, standardized and synergized extracts. Alchem's corporate endeavor has always been to know the product and build manufacturing processes around it. These could be proprietary or customized.
It prides itself in product quality and continuous ongoing research.  R&D is the company's committed focus and philosophy. The growing needs of the market are assessed, calibrated and addressed through continuous participation in trade shows. Alchem has nurtured long term relationships wing to wing both with its vendors and buyers.

www.allessa.com

Compounds of Success

Under this motto, AllessaChemie GmbH offers a comprehensive range of products and services.

Our standard program includes many chemical intermediates and specialty chemicals as so-called building blocks. Under the brand name Allessan®, we developed a number of special performance chemicals that are used by our customers directly in their applications. Last but not least, we use our comprehensive technological know-how to provide economic or qualitative advantages to our customers in exclusive syntheses.

Our portfolio is rounded off by analytics services for research, development and quality management as well as the reprocessing and refining of chemical products.

Thanks to more than 150 years of experience in the production of chemical products, service-oriented thinking and acting as well as a highly qualified staff, we are able to meet our customers’ maximum quality requirements.

www.bioiberica.com

At Bioiberica we generate ideas
and bring them to life.

This is possible because our human resources are experts in all the fields we specialize in. Enthusiasm, skill and team spirit all converge to power our company.

Through all our endeavours, in a highly motivating working environment, we produce new scientific and therapeutic advances that contribute to healthcare and enhance quality of life.

The enthusiasm and spirit of excellence of our highly specialized human resources are the true strength behind our innovation and development.

The effort and dedication of our scientific and technical personnel make it possible for Bioiberica to progress day by day, in collaboration with the most reknowned, cutting-edge research facilities and scientific institutions. All this enable us to open up new paths of investigation in each of our specialized fields.
Since our foundation in 1975, we have specialized in the research, manufacture and marketing of biomolecules for the pharmaceutical, veterinary and agricultural industries.

Our firm commitment to science and technology and our extensive knowledge of the field have consolidated our leadership as producers of Glycosami-noglycans (Mucopolysaccharides), in particular Heparin, Chondroitin Sulfate, Hyaluronic Acid and Glucosamine, as well as other active ingredients such as Amino Acids, Characterised Peptides and Hydrolysed Proteins.

 

www.biovectra.com

Who is BioVectra ?

BioVectra is the largest Canadian company manufacturing both large and small-molecule Advanced Pharmaceutical Ingredients (API’s), advanced intermediates, and cGMP bioprocessing reagents. With 40 years experience in serving the pharmaceutical and biopharmaceutical industries, our clients range from small drug development entities to many of the world’s largest multinational health care companies.

Capabilities Presentation
All of our individual manufacturing sites have been subject of regular United States FDA inspections, with the most recent audit having been completed in November, 2007. BioVectra is well-practiced in the requirements for commercialization of API's, and we currently have nine DMF’s registered with the U.S. FDA..

What Does BioVectra Specialize in?
•        Scaling Projects from development to commercial-scale under appropriate cGMPs
•        Small to Large Scale Fermentation Capabilities (up to 25,000 L)
•        Custom API Synthesis
•        Plant bioactive Extraction & Purification
•        Large-molecule animal extraction & purification, under strict BSE-Free controls
•        Synthetic modification of bioextracted compounds
•        Process-scale chromatography
•        Purification of API's from complex biological matrices
•        Specialty, bioprocessing reagents (DTT, IPTG, DTE, TCEP, etc..)
•        Bioconjugations, PEGylation and MPEG reagent production

* Combining these unique skills sets in processing drug molecules that require several of these processing techniques.

Highlights

PEG Reagents & Biconjugation

cGMP
US FDA Acceptable
Toll and Contract Mfg.

Fine Chemicals

Intermediates
APIs
Highly Potent
Pegylation
Fermentation

www.cerbios.ch

Cerbios-Pharma SA, is a privately held API manufacturer founded in 1994 by the merger of BIOFERMENT SA (founded in 1976), CERNITIN SA (founded in 1975) and SAPEC SA (founded in 1979), located in Barbengo/Lugano in southern Switzerland.

cGMP APIs made by Cerbios-Pharma SA cover small molecules (Chemical Division), large molecules and probiotics (Biological Division) sold worldwide mainly to pharma companies including EU, USA and Japan.

The chemical division has specialized in the past 30 years in Reduced Folates (world leading position) but also in the manufacturing of High Potency Active Ingredients (HPAI) with a series of Vitamin D derivatives requiring sophisticated production units with high containment levels.

The Biological Division has specialized since 1976 in research, development and production of Probiotics of Pharma quality as active pharmaceutical ingredients, pharmaceutical finished products and feed additives.
On top of that, in the last 15 years, CERBIOS has acquired a vast experience with Recombinant Proteins from mammalian cells (CHO) based on a state-of-the-art platform.

Service for third parties in exclusive manufacturing is concentrated in the area of HPAI for the Chemical Division and Recombinant Proteins for the Biological Division.
Full CMC support is given to our partners in order to provide them with the supply of cGMP clinical batches, registration/validation material and commercial manufacturing. Paramount to that is the supply of all documentation required for a successful registration.

Chemische Fabrik Karl Bucher

Chemische Fabrik Karl Bucher GmbH was established in the early 1970's and is one of today's leading manufacturers of specialty Silanes and Organic Intermediates.  During our more than 30 year history we have successfully developed an innovative and practical range of silylating agents and other organic intermediates for the chemical synthesis industry in close collaboration with global producers of pharmaceutical and agrochemical actives.

In addition to organosilicon chemistry, CFKB has developed strong expertise in fluorine, acetylene, iodine, and Grignard chemistry.  The experience and know-how we have built up over more than 30 years of challenging organic synthesis enables us to respond rapidly to customer inquiries for new compounds.   

With approximately 90 employees, we produce a range of more than 100 products in our modern facilities at our site in Waldstetten, South Germany; from laboratory up to large commercial scale.  Versatility and innovation in product development, customer service, and careful attention to product quality are key and central to our business philosophy and practices.  Being a relatively small company which is still owned and run by the founder, Mr. Karl Bucher and his family, has enabled us to maintain high flexibility that allows us to provide special services and tailor-made solutions to our customers.

Due to the highly specialized nature of our business, our customer relationships are extremely selective and important to us; we are selective and careful to ensure that mutual capabilities and expectations are defined and met in every case.  We enjoy a prestigious customer base which includes many of the major international pharmaceuticals and agrochemical producers and their sub-contractors.  We strive for the complete satisfaction of all our customers and are pleased to develop custom solutions whenever we can.

Click on Image to download
certificate in pdf format

It is our goal to continuously improve the quality of our products and services by close collaboration
with our customers to build a reliable, mutually beneficial long term relationship.

 

www.contract-chemicals.com

Contract Chemicals is a leading independent UK based manufacturer of fine and speciality chemicals. Specialising in amination, bromination, cyanation, epichlorohydrin, Friedel-Crafts and thionyl chloride chemistries, we produce a range of own multi-application products as well as offering over 25 years experience in contract manufacture.

Established in 1977, Contract Chemicals has grown significantly over the last 30 years to become a leading international supplier of fine and speciality chemicals. Our success has been achieved through a commitment to continuously improve our competitiveness, and by working to the highest levels of accreditation for quality, health and safety, environment and management systems, an essential requirement for all our customers.

Our key product markets include pharmaceutical, agrochemical, detergent, photographic, personal care, food and fragrances, all highly regulated industries characterised by an exacting requirement for quality and consistency. Products from our extensive range can be found in everything from market-leading antibiotics and anti-hypertension drugs through to photographic paper and salt and vinegar potato crisps.

Recognising the global demands of our industry, we have an extensive network of committed, professional overseas agents, who have helped us to consistently generate over 60% of annual turnover from export sales.

To remain at the forefront of specialised organics production we continue to invest in our multi-purpose manufacturing facilities located in Knowsley, UK. The headquarters site has increased total reactor capacity by over 25% in recent years, further strengthening our position as the independent contract manufacturer of choice.

www.dominospecialtyingredients.com

When you mention "Domino", visions of sugar bowls are conjured, but the story of Domino Specialty Ingredients shows how a pure and simple ingredient like sugar can be transformed.

In the modern food industry, where sugar is essential not only for sweetening but also for bulking, texture modification and other functionalities, Domino Specialty Ingredients becomes indispensable. We've progressed beyond sugar by looking at our entire line of products with a primary focus on the needs of our customers. Our research and development experts take a proactive approach from the start, so that our end product consistently performs to meet your expectations.  

Over the years, Domino Specialty Ingredients has helped our customers simplify processing, technologically perfect their unique formulas and allowed more profits to be coaxed from their markets.
We stand ready to do the same for you.

Our family of brands include Florida Crystals®, Domino Sugar®, C&H® Sugar, and Redpath Sugar®.  

Domino Specialty Ingredients manufactures a broad spectrum of organic and natural sugar, malt, molasses, honey, rice, rice syrup, rice bran, rice flour, specialty sugars, and pharmaceutical products. Let us help you find your Sweet Spot.

www.evocatal.com

Biocatalysis is the future.

evocatal is biocatalysis. Nowevocatal is a provider of enzyme technology and biocatalytical processes. The Company offers a catalog of ready-to-use enzymes (evozymes®) and chiral building blocks available in commercial quantities. Furthermore, evocatal develops biocatalysts and chemical processes, tailored to match the specific demands of our customers.

 

evozymes® are applied in API- and intermediate synthesis, as well as in the consumer goods industries, including the production and refinement of textiles, adhesives, detergents, rubber, nutrition and cosmetics.

evocatal continuously expands its technology platform to facilitate sustainable biocatalytical processes fostering the growing bio-based economy.

 

evocatal develops and produces enzymes and chiral fine chemicals.

Enzymes are natural key to chiral intermediates. They have been designed to work stereoselectively and extremely efficient under physiological conditions. evocatal makes such enzymes available for the use in the technical production of chiral fine chemicals of highest optical purity.

Our catalog comprises over 60 ready-to-use evozymes including:

- Ketoreductases/ADHs > for the production of chiral alcohols

- Transaminases > for the production of chiral amines

- Lipases/Esterases > esterification, transesterification and hydrolysis reactions

- Oxynitrilases > production of chiral amines

- C-C coupling kit > production of chiral α-hydroxyketones

- Cofactor regenerating enzymes

 

evochemicals – chiral building blocks > 99%ee

Using our high-performance biocatalysts, we produce a selection of pure chiral fine chemicals including:

- secondary alcohols

- diols

- hydroxyesters

- 2-hydroxyketones

including molecules such as:

(R)-[3,5-Bis (trifluoromethyl) phenyl] ethanol (Key intermediate of Aprepitant)

(R)-3-Quinuclidinol (Key intermediate of Solifenacine)

(R)-Methyl-3-hydroxybutyrate (R-MHB, Key intermediate for Dorzolamide)

(S,S)-2,3-Butanediol (building block for chiral ligand)

(R) / (S)-Phenylethanol

evocatal offers exclusive developments of tailor-made enzymes and chemical processes

Benefit from our strong technology platform through our contract R&D- and manufacturing services:

- screening: we find the right enzyme for your target synthesis

- enzyme engineering: we optimize enzymes to meet the requirements of your process

- process development: we develop your biocatalytic process and deliver the first kg

- enzyme supply: we guarantee supply of each developed enzyme in commercial scale

- fine chemicals production: we produce your compound in commercial quantities

Highlights:

- Development of a biocatalytic process to synthesize (R)-Methyl-3-hydroxybutyrate evolving an enzyme standing out with CP > 99% and ee > 99%. The process was transferred to CMO to produce 2.5 mt of biocatalyst.

- Replacing an established chemical process for the synthesis of (R)-3-Quinuclidinol, key intermediate for Solifenacine, evolving a powerful biocatalyst, targeting complete conversion at 99% ee.

 

 

www.rexim.fr

Evonik Industries;
Rexim Amino Acids

We are the key supplier for customers using high quality grades of amino acids and amino acid derivatives worldwide. Our core strength is to manufacture these products under cGMP and controlled hygiene conditions. It is our responsibility to customers, staff, and the environment to provide products that are safe in every respect. To achieve this goal, we have allocated all necessary resources in research and development and quality assurance. We are committed to protect the environment and to promote human health and well being.

We are committed to satisfying our customers and continually demonstrate our focus through the quality selection of raw materials, the manufacturing and supply of our products, and the processing of our customer’s orders. Customer focus is the driving force behind all of our business activities.
A wide range of quality standards allows our customers to have flexibility in the application of our products:

• Both the production sites in China and in France are ISO certified.
• The facilities have been inspected by customers and agencies including the United States Food and Drug Administration (FDA) and the European counterpart AFSSaPS.
• Most of our products are registered with Drug Master Files in Europe and the U.S. We also hold Certificates of Suitability for a number of our products.
• We are manufacturing according to HACCP requirements.
• Thanks to the change of our raw material basis to non-animal origin, we are now able to provide kosher certified materials for the majority of our products. Equally important, the products are in line with and certified according to Halal requirements.
• We provide our customers with assurances on the absence of residual solvents, allergens, and genetically modified organisms on request.
• In addition to high purity chemical grades, we offer grades with controlled levels of micro-organisms and endotoxins, especially for the nutrition and infusion applications.
• The amino acids produced and sold by Evonik Rexim SAS and Evonik Rexim (Nanning) Pharmaceutical Co., Ltd do not contain chlorinated solvents, preservatives, antioxidants, mycotoxins, aflatoxins, pesticides, hormones, dioxins, or cytotoxic compounds.

We welcome our customers to tour and audit our facilities to see our quality excellence first hand.

www.flamma.it/

Who we are

Flamma is a company specialised in the manufacture of active ingredients and intermediates for the pharmaceutical, nutraceutical and cosmetic industries, established in 1950 in Bergamo, north of Milan.
Our state of the art plant occupies more than 5000 sq. meters over an area of 38000 sq meters, allowing us further expansion possibilities.

• What we do
Our experience in the field of amino acids and related derivatives dates back to those early days, while now we manufacture also other synthetic molecules. 
Flamma’s latest ventures, as a result of market trends and some specific requests, include diversification into custom development, manufacturing of peptides and protected amino acids.
• We offer 50 years-old experience
Flamma is pleased to offer its skills in the field of amino acids derivatives and active pharmaceutical ingredients, backed up by our development and manufacturing facilities. Our 50 years-old reputation, our performance and the usual specific agreements are your gage of confidentiality and exclusivity.

 

www.formosalab.com

Formosa Laboratories, Inc. produces
APIs and UV-filters in its modern facilities near Taipei.

 

Its GMP compliance has been approved by DOH of Taiwan, US FDA, BSG of Germany, and PMDA of Japan.

Formosa’s major API products include:

• Vitamin D derivatives (Alfacalcidol, Calcitriol, Calcipotriol, Doxercalciferol, and Paricalcitol),
• Balsalazide
• Benzonatate
• Capsaicin
• Colesevelam
• Gadodiamide
• Flupentixol
• Melitracen
• Meprobamate
• Montelukast
• Mycophenolate Mofetil
• Sevelamer (HCl and Carbonate)
• and Taltirelin 

As a major producer in the world, our UV-filter products include avobenzone and Octinoxate. We also provide custom synthesis service from process development to full commercial production for APIs and other specialty chemicals, with full documentation support.

 

www.hshenglin.com

 

Henlin, a cost effective manufacturing center, is prepared to entertain customer's request for key raw materials.

 

Henlin is a privately-owned chemical manufacturing company located within North Central China in the Ji Heng Economic Zone, WuYi  District, Heng Shi City, China.  Henlin's current factory output of 1000 MT of product is being expanded by 35% and today Henlin is prepared to consider toll manufacturing opportunities.  Manufacturing assets will be implemented at the direction of the customer to manufacture products under complete customer control.

Henlin will contribute manpower, services, logistics and access to government permitting.

www.infagroup.com

INFA, since its start fifty years ago, has distinguished itself by offering first class products and services, building up a tradition of reliability, trustworthiness, and mutually beneficial long-term relationships.

Nowadays we present ourselves as a fully integrated organization that makes us quite unique in the API world, combining the technical and scientific expertise of our production units located both in Italy and Spain, Labochim, Sifavitor, Derivados Químicos and Kylolab with our worldwide marketing network, relying on offices in Italy, France, Germany, Switzerland and the US and on the financial support, offered by its major shareholder - Investitori Associati – whose target is to develop the size and activities of the Group.

Through this combination we will continue to better serve you, our customers, with the goal of maximizing opportunities for success.

www.innovassynth.com

Innovassynth Technologies (I) Ltd. formerly known as Chemicals Division of Indian Organic Chemicals Ltd. came in to existence since 1st August 2002. It is a part of the well-known business group involved in activities like polyester fiber, polymers, pre-forms, and computer software among others.

The company is catering to the needs of customers in the area of 'knowledge based R & D services' for the last 5 years, which include:

      

• Contract R & D
      
• Custom Synthesis
      
• Contract Manufacture

In a very short period the company has established its name as a reliable partner in above area of activities and has joined hands with many prestigious companies in the field. The company has identified NUCLEOSIDES as a niche area and earned reputation as a supplier of various protected Nucleosides and a partner for Process research.
 
The company is involved in business with well-known companies in various fields like pharmaceuticals, perfumes, agro chemicals, and fine and specialty chemicals. With two sites at its disposal, one already active at Khopoli near Mumbai and the other in the development stage at Chennai. It has already set up a cGMP Pilot Plant Facility where 10-15 Kg batch size is possible. It is going for US FDA approval in near future.

www.la-mesta.com

LA MESTA : CORE BUSINESS

With over 30 years of activity over France, Europe and in the US, La Mesta is a technology driven company involved in Custom Manufacturing of sophisticated chemical entities in the field of Pharmaceuticals, Cosmetics, Flavors & Fragrances, and Photo Industry.

La Mesta develops and manufactures sophisticated molecules, intermediates products and active ingredients.

Based on our expertise and equipment, we offer a flexible and comprehensive service, from process development to industrial manufacture.

The fundamental value guiding our company is the absolute respect of ethical rules. All projects are handled according to Confidentiality standards as well as respect of contracts in place.

One of the specific strengths of La Mesta team is its ability to develop, scale-up, optimize and intensify a process in order to implement the most effective solution for industrial production.

La Mesta offers 2 approaches to process evaluation :

- Traditional : batch production with reactors ranging from 50 to 27,000 liters or ;

- Non conventional : process scale-up using approach such as its continuous reaction system : RAPTOR ®.

www.hlchem.com

 

Lianhe Chemical Technology Co., Ltd.

Lianhe Chemical Technology Co., Ltd.— the former Huangyan Lianhe Chemical Factory, was established in 1985.The headquarter of the company is located in a scenic and seaside city—Taizhou, Zhejiang in the southeast China. Its subsidiary companies and joint stock companies mainly spread in Taizhou of Zhejiang province, Shanghai and Yancheng of Jiangsu province. Lianhe Technology is mainly engaged in chemical production and providing custom manufacturing services from various industrial including pharmaceutical, pesticides and other fine chemicals, which ranges from the quantities of lab scale to commercial production. More than 80% of our products and services are exported to USA, EU countries and Japan. In 2007 the company's turnover was USD 142.8 Million and became the top 1 enterprise on Huangyan district, Taizhou city. The tax and profit and the exporting amount reaches at a historical level.
For two decades, guided by the concept of "Striving for the first", the devoted Lianhe people have the courage to exploit and innovate continuously, thus made great contributions to the growth of our company. At present our company occupies a land area of 343,400 square meters. The Headquarter and Lianhua Pharmaceutical in Huangyan focuses on producing API & Pharmaceutical Intermediate and other specialty chemicals. Jiangsu Lianhe Chemical Technology Co. mainly produces pesticides& pesticides intermediate Company was accredited for the certifications of ISO9001:2000 quality management, ISO14001:1996 environmental management & OHSAS18001. The business management system is strictly following the international standard. All these have set up a solid basis for exploiting the international market and building-up an excellent client networks.

Always abiding by the strategy principle of "relying on science & technology talent to prosper the factory", Lianhe Technology improves greatly the science & technology content of products with great exertion and continuously recruits various types of technical employees which have accounted for 24% of the total employees. In recent 3 years, our company has completed many provincial-level science & technology development projects, among which there are three state-level new products. Our company was also appraised as "Provincial New High-tech Enterprise", "The Five-One-Group Enterprise in Zhejiang Province" as well as "Key High-tech Enterprise of State Torch Program" by Ministry of science & technology.

With the deepening of economic globalization, Lianhe Technology is committed to adapting ourselves to changes of global market , making progress by innovation and exploiting, establishing an advanced fine chemical custom manufacturing base in Asia-Pacific area or even in the world.

 

www.micro-macinazione.com

Micro-Macinazione SA was established in 1970, as an engineering company for jet-mill technology development.

In 1975, the first factory for custom micronization services was built, in Monteggio and in 1999 we started the activity on a second factory in Madonna del Piano, built following the highest current GMP state of the art and under surpevision of the Swiss Autority (Swissmedic) and the US Food and Drug Administration (FDA).

Now Micro-Macinazione SA is the european micronization leader of bulk active ingredients for the pharmaceutical industry.

Micro-Macinazione works closely with the foremost multinational pharmaceutical industries, taking an active part from the early development stages of a new project through to, and including, industrial production.

 

www.microtheraps.com

Micro Therapeutic Research Labs (MTR) is a quality driven, full service Clinical Research Organization (CRO) that provides a broad range of clinical research services to the global pharmaceutical and biotechnology industry.
Situated in Chennai, the southern part of India, Micro Therapeutic Research Labs offers world-class services in compliance with GLP and cGMP that are robust and can be customized for your unique research requirements.

At MTR, we operate with state-of-the art research facilities, offering over 240 beds to reduce cycle times for our customers and accelerate the delivery of life-enhancing drugs to market. We cater to all your needs for bioavailability / bioequivalence studies, clinical research, statistical reporting and data management.

MTR has leading, highly regarded experts in their fields. So, you’ll find we understand your goals, and develop innovative, tailor-made approaches to streamline your study and make it more cost effective.

www.musashino.com

As the leading manufacturer of lactic acid, alanine and pyruvic acid, Musashino Chemical Laboratory has fulfilled our mission with over a half century of accumulated research, development and production technology, using environmentally friendly facilities to produce high-quality products that keep a fine balance between the needs of the human race and the environment for various forms of life.
* Combining these unique skills sets in processing drug molecules that require several of these processing techniques.

http://www.nipponrika.jp/en/ 

A motto of NIPPON RIKA is "to respect our clients". 
We promise to provide the best quality and service.

The amino acid is a source of life.  We, Nippon Rika, paid its attention to amino acids from the beginning of a busines time and started amino acid production ahead of the world.  Thereafter, we supply amino acids of high quality to various countries in the world as medical supplies / food / cosmetics use.

We are active in search of unlimited possibility on extension of amino acids; making use of their characteristics as well as supply of material.

• Business Field
• Manufacture and sale of Amino Acids (Cystine, Cysteine, Tyrosine, Serine, etc.)
• Manufacture and sale of Amino Acid Derivatives
• Contract of manufacturing bulk pharmaceutical chemicals, intermediates, and investigational drugs
• Collaboration on the development of new materials

 

www.novolyte.com

Novolyte Technologies is a world leading manufacturer and supplier of specialty electrolyte materials, high performance solvents, aryl phosphorus derivatives, and technically demanding custom manufactured products. Headquartered in Cleveland, Ohio, Novolyte serves the needs of our diverse, international customers through two state-of-the-art, ISO-certified manufacturing facilities located in Baton Rouge, Louisiana and Suzhou, China. We are committed to corporate responsibility in all of our communities.

With over 50 years of innovation, our dedicated team at Novolyte has developed sustainable technologies that power solutions for our customers. Novolyte's products are used in a wide array of demanding applications around the world.

Our advanced Purolyte® electrolyte solutions are used in both disposable lithium batteries and rechargeable lithium-ion batteries found in across a broad spectrum of applications including pacemakers, portable electronic devices, and newly developing electric and hybrid electric vehicles. In addition to lithium battery electrolytes, Novolyte's ultracapacitor electrolytes are helping to advance energy storage solutions that will enable broader usage of power produced by solar arrays and wind farms, and help utilities maximize efficiencies of existing facilities to avoid building new plants.

Novolyte's specialty solvents provide advantaged products that are used in a multitude of applications that continue to grow. Our line of solvents provides a range of benefits that find use in everything from broad industrial applications to making cancer treatment drugs to specialized processes such as gold recovery. Our new green solvents are replacing less environmentally friendly alternatives in emissive applications such as printer inks, coatings, and cleaning materials.
Novolyte's Specialty Materials include our custom synthesis business and a line of aryl phosphines. The latter find use as building blocks for a variety of specialty applications such as pharma intermediates and ligands and as additives that improve the strength of Nylon airbags in automobiles or increase the color fastness of carpets. The customs synthesis business provides unique services to our customers including high-pressure custom manufacturing capabilities.

We service our customers from our state-of-the-art manufacturing plants in Baton Rouge, Louisiana USA and Suzhou, China as well as distribution centers located around the globe. We serve our European customers through our strong distributor relationship with Barentz NV. The business is dedicated to sustainable technologies and has demonstrated our commitment to moving toward reduced environmental impact through projects such as landfill gas usage or process changes that reduce waste

www.rbltd.co.uk

Speciality Chemicals Manufacturer

Established in 1869, we are today one of the UK's largest independent manufacturers of speciality organic chemicals.

Working to the latest ISO 9000:2008 standards, we offer contract manufacture and custom synthesis from kilo to multi-tonne scale, with particular expertise in:

•        Catalytic Hydrogenation including chiral hydrogenation
•        Organosulphur chemistry including carbon disulphide and thiolation
•        Reactions with Hazardous Reagents including bromine and chlorosulphonic acid

Our site in the West Midlands includes Kilo-Lab and Pilot Plant units plus over 200,000L of production scale capacity to enable seamless progression of new projects from development to commercial manufacture.

In addition, we offer a wide range of proprietary intermediates for a diverse selection of markets:

•        Pharmaceutical and veterinary intermediates to cGMP as appropriate
•        Agrochemical intermediates
•        Chemicals for the cosmetic industry, including depilatory and hair dye sectors
•        Photographic chemicals and intermediates for traditional and digital imaging including ink jets
•        Intermediates for food and beverage products and flavour and fragrance additives
•        Gas odorants
•        Alkanethiols for nanotechnology applications
•        Vulcanisation accelerators and protective agents for niche rubber applications
•        Speciality Polymer chemicals and effect additives, modifiers and protection systems.

Whilst retaining many of the traditional values inherited through the years, RBL is a modern and sophisticated operation dedicated to providing innovative solutions to the world's leading innovators

Your Enquiries are welcomed from kilo to multi-tonne volumes.

 

www.jinchengpharm.com

 

 

www.simafex.com

Simafex is a fine chemicals company with a worldwide presence. 

Founded in 1959 near La Rochelle in west France, it was part of Pierre Fabre laboratories till 1987 when it joined the French pharmaceutical group Guerbet.

Years of working in close cooperation with leading pharmaceutical companies worldwide have made us a valuable partner for the synthesis of new molecules.

Our main activity is concentrated on the custom synthesis and toll manufacture of advanced intermediates and active ingredients for the pharmaceutical industry.

We offer scale-up services for both new molecules in the early phase of development and compounds awaiting approval in the registration phase.

 A powerful combination of know-how and experience have won us the confidence of customers and enabled us to construct long lasting partnerships.

Thanks to the successful driving of major projects and a dynamic investment policy, recent years have seen a significant growth rate for Simafex.

 

www.syncom.nl/hr/index.html

Syncom is a privately-owned contract research organization that specializes in all aspects of organic synthesis.  We focus primarily on the pharmaceutical industry although we are also active in organic materials and work for the electronics and photo industries.  We are well known for our special expertise and experience in the resolution of racemates with the aid of the patented technology known as Dutch Resolution.   

A sampling of some of our expertise include:

• Resolution of racemates
• Synthesis of enantiopure compounds / Stereospecific synthesis
• Synthesis of reference standards, metabolites, and impurities
• Synthesis of scaffolds and building blocks
• Steroid and Vitamin D analogue synthesis
• Focused Libraries
• Carbohydrate Synthesis
• Materials
• Process Research / Route Optimization
• Catalysis
• Lead Optimization

www.zannanpharma.com

Zannan Pharma, Ltd. is a custom synthesis and contract R&D company based in Shanghai, China.

With the expertise in custom synthesis, FTE contract research, and process development, Zannan provides high-quality services with competitive prices to our customers. As a custom synthesis and contract R&D company, in addition to quality assurance and timeline control, Zannan strictly executes the regulations of IP protection for our customers, which in turn has rewarded Zannan with satisfied and long term customers’ contracts from US, Europe, and Japan.

With 102 hoods in ~30,000 ft2 of lab space in two buildings, Zannan’s research and production units are facilitated with state-of-the-art QA/QC including NMR, LC/MS, HPLC, GC, etc. Equipped with 2 x 50 L, 1 x 30 L reactors and temperature ranged over -75o ~ 180o C, Zannan is capable of producing up to ~50 kg of wide ranges of reaction products in Shanghai site, whereas the production size >50 kg can be done in Zannan’s contracted facility in Zhejiang. As to the people, Zannan’s R&D team is formed by >50% Ph.D.’s and masters from top-tier institutions in China and led by experienced scientists who obtained Ph.D. from top American universities and worked in international pharma’s for many years in drug discovery, process development, catalysis, and polymerization technology.

Currently, Zannan provides: (1) “Zhan (Ru) Catalysts” highly active for metathesis reactions; (2) High-quality API intermediates and catalog products; (3) Custom synthesis and FTE contract research from lab-scale to pilot; (4) Process R&D and manufacturing in China, which would facilitate the drug discovery and process development for our customers to save their efforts, time, and cost. Moreover, Zannan Chemists also focus on development of the synthetic routes and methodologies (e.g., Zhan Catalysts for metathesis reactions, e.g., RCM (ring-closing metathesis), CM (cross-metathesis), ROMP (ring-opening metathesis polymerization), etc. for customer R&D projects.

www.zeon.co

Since the establishment of ZEON Corporation in 1950, we have consistently taken advantage of our original technologies and created numerous unique products that cannot be imitated by any other company.

We intend to continue contributing to society through our world-class technologies and products, with particular emphasis on responding rapidly and valuing open communication.

Even in today's business environment, marked by increasingly intense, worldwide, borderless competition, we will steadfastly pursue improvement and reform to continue offering products that customers can count on for quality.

We will also protect the global environment as an exemplary corporate citizen and create new businesses by proactively identifying the needs of the society and cultivating the seeds of future opportunities.

We deeply appreciate your ongoing support and encouragement for ZEON Corporation.

Segment	Core Products
Elastomer Business	Synthetic rubbers, synthetic latices, chemicals (C5 petroleum resins, thermoplastic elastomers, etc.)
Specialty Materials Business	Specialty chemicals (synthetic aroma chemicals, industrial chemicals, etc.), information materials (elastromics materials, polymerized toners, etc.), specialty plastics (cyclo-olefin polymers, optical materials, etc.)
Others	RIM formulations, RIM products, medical products, butadiene extraction technology, PVC manufacturing, PVC compounds, packing materials, housing materials, etc.)

 

 

www.zuchem.com

The zuChem Mission
zuChem develops proprietary technologies for the manufacture of glycochemicals for use in the food, specialty and fine chemical markets. The zuChem approach is unique, combining new proprietary technologies with the more traditional synthetic techniques. zuChem researchers have a proven track record in developing and implementing scalable, industrial quality processes.
Glycochemicals are key components of many drugs and drug intermediates. Many are impractical or even impossible to make using current chemical production methods, resulting in high cost and limited availability. Because of this, their use has been restricted in drug discovery and development. Our focus on the synthesis of these compounds will enable the discovery of new drugs, particularly antimicrobials, anti-virals, and anticancer compounds. Our proprietary synthesis methods also reduce the production costs of many glycochemical-based specialty and fine chemical products.

The Importance of Sugars and Carbohydrates
Sugars are among the most fundamental chemicals found in nature. They are important in human health, nutrition, and in the regulation of a variety of processes in our bodies. In nature, certain sugars are made in large quantities through a series of complex biochemical reaction.
While industry has been able to extract these sugars to make commodity products, such as table sugar, modifying them by traditional chemistry methods has proven either too expensive or impossible for all except the simplest of modifications.
For decades researchers have known there was a tremendous commercial opportunity to be unlocked by making and modifying sugars. Products like the sweetener sucralose or the pharmaceutical building block L-ribose represent the tip of the iceberg of the commercial opportunity for glycochemicals products. Despite their biological and commercial importance, the scaleable, inexpensive production of such non-commodity sugars has been extremely difficult to date. With new breakthroughs in biotechnology and chemistry, the promise of glycotechnology is now within reach.

zuChem Technology Platform
zuChem’s technology platform is a combination of proprietary process technology and know-how which is equally useful in the production of nutritional/food ingredients and in pharmaceutical discovery programs. The Company converts commodity chemicals into a series of sequentially higher-value products. zuChem has chosen to focus on the nearer-term chemicals opportunities and has segregated the drug opportunities into zuSyn, a wholly owned subsidiary of zuChem. This is because of differing risk/reward profiles, time to market, and investment strategies in the pharmaceutical area. The Company plans on financing zuSyn separately once it has met certain development milestones. This document focuses on zuChem’s opportunities with respect to the core technology platform and its applications in the food ingredients and fine chemicals/pharmaceuticals intermediates markets.